Peptide Therapy Guide

Explore educational information about listed peptide therapies. This content is not medical advice.

A reading room, not a recommendation engine

Start with context

Peptide terminology can be dense and the evidence can vary by substance and use. Use these entries to orient your research, then take your questions to a qualified healthcare professional.

Browse entries

152 entries currently available in the directory.

Growth Hormone, Muscle & Performance

ACE-031

A myostatin inhibitor studied for muscle-wasting conditions and muscular dystrophy.

Growth Hormone, Muscle & Performance

ANP

Atrial Natriuretic Peptide, studied for its role in fat metabolism and cardiovascular function.

Metabolic, Weight Loss & GLP-1

AOD-9604

A modified fragment of human growth hormone studied for fat metabolism and body composition.

Healing, Repair & Regenerative

ARA-290

An erythropoietin-derived peptide studied for tissue protection and neuropathic pain relief.

Healing, Repair & Regenerative

Ac-SDKP

A tetrapeptide that inhibits fibrosis and promotes cardiac and renal tissue repair.

Metabolic, Weight Loss & GLP-1

Amylin

A hormone co-secreted with insulin that helps regulate glucose levels and promotes satiety.

Tissue Repair

BPC-157

BPC-157 is an experimental peptide. Learn what limited human research can tell us, FDA safety concerns, and why claimed benefits remain uncertain.

Anti-Aging

CJC-1295

CJC-1295 has limited clinical safety data. FDA reports potential immunogenicity and serious adverse events associated with its use.

Growth Hormone, Muscle & Performance

CJC-1295 (DAC)

A growth hormone-releasing hormone analog with Drug Affinity Complex for extended half-life and sustained GH elevation.

Metabolic, Weight Loss & GLP-1

Cagrilintide

A long-acting amylin analog being studied in combination with semaglutide for enhanced weight management.

Cognitive, Mood & Sleep

DSIP

Delta Sleep-Inducing Peptide, a natural peptide that promotes deep, restorative sleep.

Cognitive, Mood & Sleep

Dihexa

A powerful cognitive-enhancing peptide derived from angiotensin IV that promotes synaptogenesis.

Metabolic, Weight Loss & GLP-1

Dulaglutide

A once-weekly GLP-1 receptor agonist for type 2 diabetes management and cardiovascular risk reduction.

Longevity, Anti-Aging & Mitochondrial

Epitalon

A tetrapeptide that may activate telomerase and promote cellular longevity.

Longevity, Anti-Aging & Mitochondrial

FOXO4-DRI

A peptide that selectively induces apoptosis in senescent cells for rejuvenation.

Healing, Repair & Regenerative

GHK-Cu

A copper peptide with powerful regenerative properties for skin, hair, and connective tissue.

Growth Hormone, Muscle & Performance

GHRP-2

A potent growth hormone-releasing peptide that also stimulates appetite and cortisol release.

Growth Hormone, Muscle & Performance

GHRP-6

A growth hormone-releasing peptide known for strong GH release and significant appetite stimulation.

Metabolic, Weight Loss & GLP-1

GIP Analog

Glucose-dependent insulinotropic polypeptide analogs that enhance insulin secretion and may aid weight management.

Growth Hormone, Muscle & Performance

Ghrelin

The hunger hormone that stimulates appetite and growth hormone release from the pituitary.

Metabolic, Weight Loss & GLP-1

Glucagon

A pancreatic hormone that raises blood glucose and is being studied in combination therapies for weight loss.

Growth Hormone, Muscle & Performance

Hexarelin

A powerful synthetic GHRP with cardioprotective properties beyond growth hormone stimulation.

Longevity, Anti-Aging & Mitochondrial

Humanin

A mitochondrial-derived peptide with cytoprotective effects against age-related diseases.

Growth Hormone, Muscle & Performance

IGF-1

Insulin-like Growth Factor 1, a key hormone mediating many of growth hormone's anabolic effects.

Growth Hormone, Muscle & Performance

IGF-1 DES

A truncated IGF-1 variant with increased potency and localized effects at injection sites.

Growth Hormone, Muscle & Performance

IGF-1 LR3

A long-acting IGF-1 variant with extended half-life and enhanced potency for muscle growth.

Anti-Aging

Ipamorelin

Ipamorelin safety evidence is limited and route-specific. FDA identifies potential immunogenicity and insufficient information for some injection routes.

Healing, Repair & Regenerative

KPV

A tripeptide derived from alpha-MSH with potent anti-inflammatory and antimicrobial properties.

Healing, Repair & Regenerative

LL-37

An antimicrobial peptide with wound healing, immune modulation, and anti-biofilm properties.

Metabolic, Weight Loss & GLP-1

Leptin

The satiety hormone that regulates energy balance and appetite through hypothalamic signaling.

Metabolic, Weight Loss & GLP-1

MOTS-c

A mitochondrial-derived peptide that regulates metabolic homeostasis and may mimic exercise benefits.

Metabolic, Weight Loss & GLP-1

Mazdutide

A dual GLP-1/glucagon receptor agonist in development for obesity and fatty liver disease treatment.

Cognitive, Mood & Sleep

Noopept

A peptide-derived nootropic compound that enhances memory, learning, and neuroprotection.

Cognitive, Mood & Sleep

PACAP

Pituitary Adenylate Cyclase-Activating Polypeptide with neuroprotective and cognitive effects.

Growth Hormone, Muscle & Performance

PEG-MGF

Pegylated MGF with extended half-life for systemic muscle growth and recovery support.

Sexual Health

PT-141

Bremelanotide's Vyleesi label covers a specific sexual-desire disorder in premenopausal women, not general sexual enhancement.

Metabolic, Weight Loss & GLP-1

Pramlintide

An FDA-approved amylin analog used alongside insulin for diabetes management and appetite control.

Metabolic, Weight Loss & GLP-1

Retatrutide

A triple agonist targeting GLP-1, GIP, and glucagon receptors for potentially superior weight loss outcomes.

Longevity, Anti-Aging & Mitochondrial

SHLP-1

Small Humanin-like Peptide 1, a mitochondrial peptide involved in cellular protection.

Longevity, Anti-Aging & Mitochondrial

SHLP-2

Small Humanin-like Peptide 2, associated with insulin sensitivity and metabolic regulation.

Longevity, Anti-Aging & Mitochondrial

SHLP-3

Small Humanin-like Peptide 3, involved in mitochondrial function and cellular health.

Longevity, Anti-Aging & Mitochondrial

SHLP-4

Small Humanin-like Peptide 4, with potential anti-inflammatory and protective effects.

Longevity, Anti-Aging & Mitochondrial

SHLP-5

Small Humanin-like Peptide 5, contributing to mitochondrial-nuclear communication.

Longevity, Anti-Aging & Mitochondrial

SHLP-6

Small Humanin-like Peptide 6, playing a role in cellular stress responses.

Dermatology, Hair & Cosmetic

SNAP-8

An octapeptide that inhibits muscle contraction for wrinkle reduction similar to Argireline.

Cognitive, Mood & Sleep

Selank

An anxiolytic and nootropic peptide based on tuftsin with immune-modulating properties.

Weight Management

Semaglutide

Semaglutide: understand product-specific approved uses, weight-loss trial results, important safety warnings, and questions for your prescriber.

Cognitive, Mood & Sleep

Semax

A synthetic peptide derived from ACTH with nootropic, neuroprotective, and cognitive-enhancing effects.

Anti-Aging

Sermorelin

Sermorelin has a historical Geref approval context. That history does not establish FDA approval of current compounded anti-aging products.

Healing, Repair & Regenerative

TB-500

A synthetic version of Thymosin Beta-4 promoting wound healing, tissue repair, and flexibility.

Growth Hormone, Muscle & Performance

Tesamorelin

An FDA-approved GHRH analog for reducing visceral adipose tissue in HIV patients with lipodystrophy.

Tissue Repair

Thymosin Beta-4

Thymosin beta-4 and products called TB-500 need careful identification. Experimental recovery claims are not established treatment recommendations.

Immune, Inflammation & Autoimmune

Thymulin

A thymic hormone that regulates T-cell development and immune system function.

Weight Management

Tirzepatide

Tirzepatide: read about Zepbound's approved uses, clinical evidence, safety warnings, oral contraceptive interactions, and prescribing questions.

Immune, Inflammation & Autoimmune

VIP

Vasoactive Intestinal Peptide with anti-inflammatory and immunomodulatory properties.

Questions worth carrying forward

  • What is known about the specific substance and use being discussed?
  • What uncertainties, interactions, or contraindications should be reviewed?
  • Who is responsible for evaluation, prescribing where applicable, and follow-up?